目的:观察祛风宣肺止咳汤联合西药治疗咳嗽变异性哮喘的临床疗效。方法:将咳嗽变异性哮喘患者120例随机分为2组各60例,对照组给予沙美特罗替卡松粉吸入剂,观察组在对照组基础上加用祛风宣肺止咳汤,2组均连续治疗3月,比较2组临床疗效、治疗前后症状积分,观察治疗期间药物不良反应、随访1年后复发率。结果:总有效率观察组为98.33%,对照组为86.67%,2组比较,差异有显著性意义(P<0.05)。2组患者治疗前症状积分比较,差异无显著性意义(P>0.05),治疗后2组患者症状积分较治疗前显著降低(P<0.05),治疗后观察组症状积分显著低于对照组(P<0.05)。随访1年,观察组复发11例(18.33%),对照组复发32例(53.33%),2组比较,差异有显著性意义(P<0.05)。结论:祛风宣肺止咳汤联合西药治疗咳嗽变异性哮喘其疗效显著,能够有效改善患者临床症状,安全可靠,降低复发率,值得临床推广运用。 Objective: To observe the clinical efficacy of Qufeng Xuanfei Zhike Decoction combined with western medicine in treating cough variant asthma. Methods: One hundred and twenty patients with cough variant asthma were randomly divided into 2 groups of 60 patients. The control group was given salmeterol and fluticasone powder inhalation. The observation group was given Qufeng Xuanfei Zhike Decoction on the basis of the control group. All the patients were continuously treated for 3 months. The clinical efficacy, symptom scores before and after treatment were compared between the two groups. The adverse drug reactions during the treatment were observed, and the recurrence rate was observed after one year. Results: The total effective rate was 98.33% in the observation group and 86.67% in the control group. There was significant difference between the two groups (P <0.05). There was no significant difference in symptom scores between the two groups before treatment (P> 0.05). After treatment, the symptom scores of two groups were significantly lower than those before treatment (P <0.05). After treatment, symptom score of observation group was significantly lower than that of control group P <0.05). After one year of follow-up, 11 cases (18.33%) in the observation group and 32 cases (53.33%) in the control group showed recurrence. There was significant difference between the two groups (P <0.05). Conclusion: Qufeng Xuanfei Zhike Decoction combined with Western medicine in the treatment of cough variant asthma has significant curative effect, which can effectively improve the clinical symptoms, safety and reliability and reduce the recurrence rate, worthy of clinical application.