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目的探讨全胃切除术和近端胃切除术治疗贲门癌后生存期及并发症的差别。方法将245例贲门癌患者分为两组,其中全胃切除术组(total gastrectomy TG组)176例,近端胃切除术组(proximal gastrectomy PG组)69例。结果 TG组患者3、5年生存率分别为44.6%和24.5%,PG组为分别30.2%和17.7%,2组患者的3、5年生存率差异有显著性(P<0.05)。TG组术后并发症的发生率为6.5%,PG组为29.7%。2组并发症发生率差异有统计学意义(P<0.05)。结论相对于近端胃切除术,全胃切除术治疗贲门癌可明显降低术后并发症的发生率,提高远期治疗效果。
Objective To investigate the difference of survival and complications between total gastrectomy and proximal gastrectomy for cardia cancer. Methods 245 patients with cardiac cancer were divided into two groups: 176 cases in total gastrectomy TG group and 69 cases in proximal gastrectomy PG group. Results The 3- and 5-year survival rates were 44.6% and 24.5% in the TG group and 30.2% and 17.7% in the PG group respectively. There was a significant difference between the two groups in the 3-and 5-year survival rates (P <0.05). The incidence of postoperative complications was 6.5% in the TG group and 29.7% in the PG group. The incidence of complications in the two groups was statistically significant (P <0.05). Conclusion Compared with proximal gastrectomy, total gastrectomy for cardia cancer can significantly reduce the incidence of postoperative complications and improve the long-term therapeutic effect.