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目的 :研究建立兔实验性葡萄膜炎模型的方法,为葡萄膜炎的实验研究提供一种有用的实验动物模型,为后续的深入研究提供基础资料。方法 :结合临床,对近年来葡萄膜炎动物造模文献的研究进展进行讨论分析总结。结果 :通过对兔不同类型、不同造模方法的研究分析、对比统计,制定出比较标准的葡萄膜炎动物模型的复制方法。结论本研究建立了用牛血清白蛋白(bovine serum albumin,BSA)作异体抗原,玻璃体、耳缘静脉2次注射法诱导兔实验性葡萄膜炎动物模型[1]。注入的动物模型,为进一步研究葡萄膜炎提供资料。
Objective: To study the method of establishing a rabbit experimental uveitis model, to provide a useful animal model for the experimental study of uveitis and to provide the basic data for further research. Methods: In combination with clinical, the progress of the research on animal modeling of uveitis in recent years is discussed and analyzed. Results: According to the research and analysis of different types of rabbits and different modeling methods, comparative statistics were made to establish the replication method of the comparative standard uveitis animal model. Conclusion This study established a bovine serum albumin (bovine serum albumin, BSA) as allogenic antigen, vitreous, the ear vein 2 rabbits induced experimental rabbit uveitis animal model [1]. Injected animal model for further study of uveitis data.