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目的探讨儿童精神分裂症的预后及其影响因素。方法收集2005年8月1日-2007年7月31日在我院首次住院(年龄≤18岁)经CCMD-3诊断为精神分裂症的患者184例,采用临床总体印象量表(疾病严重程度CGI-S)、个人和社会功能量表(PSP)及自制调查表,随访与量表现场测评相结合的方法获得资料,最后完成随访的患者164例,脱落20例。结果经χ2检验分析得出女性患者的复发率较男性患者低(χ2=8.89,P<0.05),女性患者的社会功能恢复状况较男性患者好(χ2=10.62,P<0.05)。经多元回归分析显示,影响预后的主要因素有:CGI得分、居住地、自知力恢复程度、是否为独生子女。结论女性儿童精神分裂症预后较男性好,CGI得分越高的患者社会功能越差,居住在城市、自知力恢复好、是独生子女的患者预后较好。
Objective To investigate the prognosis of schizophrenia in children and its influencing factors. Methods A total of 184 patients diagnosed as schizophrenia by CCMD-3 in our hospital from August 1, 2005 to July 31, 2007, were enrolled in this study. The clinical overall impression scale (severity of disease CGI-S), personal and social function scale (PSP) and self-made questionnaire, follow-up and on-site measurement methods to obtain information, and finally completed the follow-up of 164 patients, 20 cases off. Results The χ2 test showed that the recurrence rate of female patients was lower than that of male patients (χ2 = 8.89, P <0.05). Female patients had better social function recovery than male patients (χ2 = 10.62, P <0.05). Multiple regression analysis showed that the main factors affecting the prognosis are: CGI score, place of residence, knowledge of the degree of recovery, whether it is only child. Conclusions The prognosis of schizophrenia in female children is better than that of men. The higher the score of CGI, the worse social function, living in the city, the better self-knowledge, and the prognosis of one-child children is better.