帕金森病是一种因黑质、纹状体神经元变性、数目减少引起的主要危害中、老年人的神经变性性疾病，迄今为止其发病机理仍未完全清楚。本文综述了黑质、纹状体的一般结构，纤维联系及其突触构筑，同时简述了帕金森病的发病机理 Parkinson’s disease is a neurodegenerative disease caused by the degeneration of substantia nigra and striatal neurons and the reduction of the number. Neurodegenerative diseases of the elderly are still unknown. Up to now, the pathogenesis of Parkinson’s disease remains unclear. This review summarizes the general structure of the substantia nigra and striatum, the connections between the fibers and their synapses, and at the same time a brief description of the pathogenesis of Parkinson’s disease