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人绝经期促性腺激素(hMG)治疗继发闭经国内报道不多。现将我们联合使用上海生物化学研究所上海生物制品研究所协作研制的人绝经期促性腺激素(hMG)治疗继发闭经的临床结果报道如下。资料与方法一、一般资料:自1986年1月至1988年2月应用国产hMG 治疗17例继发闭经,其中席汉氏综合征9例,西蒙氏综合征1例,多囊卵巢综合征2例,部分垂体功能不全性闭经5例。17例闭经时间1～9年,平均4年。其中原发不孕4例,有足月分娩史者13例。用药前分别测定FSH、LH、T_3、T_4、17KS、17OH、E_2、PRL 及阴道细胞周期涂片。选择对象均属垂体功能不全或部分功能失调及雌激素水平偏低而泌乳激素正常者。二、方法:首先行人工周期疗法,于月经周期第5～6天起每日肌注hMG 1支(内含FSH75IU,
Human menopausal gonadotropin (hMG) treatment of secondary amenorrhea is not reported in the country. Now we use the Shanghai Institute of Biochemistry Shanghai Institute of Biological Products collaborative development of human menopausal gonadotropin (hMG) for the treatment of secondary amenorrhea clinical results are reported below. Materials and Methods First, the general information: From January 1986 to February 1988 application of domestic hMG treatment of 17 cases of secondary amenorrhea, including Sean’s syndrome in 9 cases, 1 case of Simon’s syndrome, polycystic ovary syndrome 2 Cases, some pituitary dysfunction amenorrhea in 5 cases. 17 cases of amenorrhea for 1 to 9 years, an average of 4 years. Of which 4 cases of primary infertility, full-term delivery history in 13 cases. FSH, LH, T_3, T_4, 17KS, 17OH, E_2, PRL and vaginal cell cycle smear were measured before treatment. Select objects are pituitary insufficiency or partial dysfunction and low estrogen levels and lactation normal. Second, methods: first line of artificial cycle therapy, menstrual cycle in the first 5 to 6 days since the daily intramuscular hMG 1 (containing FSH75IU,