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本文通过对48例住院化疗肺结核患者的体液免疫水平进行为期4~5个月的监测,发现:接受标准化疗后的肺结核患者产生3种不同的体液免疫反应模式:66.6%的肺结核患者接受化疗后,其血清抗结核IgG抗体在较高水平上持续升高,经1~3个月达到最高值,然后平缓下降;18.7%的肺结核患者在化疗后,其血清特异性IgG抗体维持较高水平,无升高后平缓下降,或在阳性值上下维持不变;还有14.6%的患者,血清特异性抗体水平低,接受化疗后不产生体液免疫反应。有5例肺结核患者其血清特异性抗体水平在观察期间呈现周期性波动。本研究结果表明:化疗作用下结核患者体液免疫增强反应具有保护性效应
In this paper, we monitored the humoral immunity of 48 patients with chemotherapy-induced pulmonary tuberculosis for 4-5 months and found that there were 3 different modes of humoral immune response after receiving standard chemotherapy: 66.6% of tuberculosis patients accepted After chemotherapy, the serum anti-TB IgG antibody increased continuously at a higher level and reached the highest level in 1 to 3 months and then decreased gently. After chemotherapy, 18.7% of the patients with tuberculosis maintained their serum-specific IgG antibodies Higher level, no increase after a gentle decline, or in the positive and negative values remain unchanged; and 14.6% of patients, serum-specific antibody levels are low, after receiving chemotherapy does not produce humoral immune response. Serum specific antibody levels in 5 patients with tuberculosis showed periodic fluctuations during the observation period. The results of this study show that the humoral immune response to chemotherapy in tuberculosis patients has protective effect