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27例急性心肌梗塞患者用链激酶溶栓治疗,其中20例联合静脉滴注乙酰半胱氨酸(NAC)。结果显示:联合应用NAC治疗后血浆还原型谷胱甘肽(GSH)及GSH与氧化型谷胱甘肽(GSSG)之比(GSH/GSSG)显著性增高(P<0.05),伴随GSSG显著性降低(P<0.05)。NAC治疗组心指数亦明显高于对照组(P<0.01)。
Thirty-seven patients with acute myocardial infarction were treated with streptokinase thrombolysis, 20 of whom received intravenous acetylcysteine (NAC). The results showed that the plasma reduced glutathione (GSH) and the ratio of GSH to GSSG (GSH / GSSG) were significantly increased (P <0.05) after NAC treatment in combination with GSSG Significantly decreased (P <0.05). NAC treatment group heart index was significantly higher than the control group (P <0.01).