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目的:探讨分析非小细胞肺癌术前辅助化疗的疗效。方法:选取非小细胞肺癌患者70例,在征求患者家属同意的情况下分为观察组和对照组,每组患者各35例。观察组术前进行辅助化疗后进行手术,对照组直接进行手术。比较两组患者的疗效。结果:观察组辅助化疗有效率为51.4%。观察组患者手术的切除率为85.7%,对照组患者手术的切除率为71.4%。对患者术后1年和术后3年生存率进行跟踪记录,观察组患者术后1年存活率为74.3%,术后3年存活率为37.1%.对照组患者术后1年存活率为62.9%,术后3年存活率为28.6%。两组在手术切除率、术后1年存活率、术后3年存活率方面比较有显著差异(P<0.05)。两组均无不良事故(术中死亡、手术并发症)发生,两组在不良事故发生情况比较,P>0.05,无显著性差异。结论:非小细胞肺癌术前辅助化疗疗效显著,能够提高手术切除率和术后存活率,值得临床推广。
Objective: To investigate the effect of preoperative adjuvant chemotherapy in non-small cell lung cancer. Methods: Seventy patients with non-small cell lung cancer were selected and divided into observation group and control group with the consent of their relatives. 35 patients in each group. The observation group received surgery before adjuvant chemotherapy and the control group received surgery directly. Compare the efficacy of two groups of patients. Results: The effective rate of adjuvant chemotherapy in observation group was 51.4%. Surgical resection rate was 85.7% in the observation group and 71.4% in the control group. One year after surgery and 3-year survival rate were recorded and recorded, the survival rate of one year after operation in the observation group was 74.3%, and the survival rate at 3 years after operation was 37.1% .The one-year survival rate in the control group was 62.9%, 3-year survival rate was 28.6%. There was significant difference between the two groups in surgical resection rate, 1-year postoperative survival rate and 3-year postoperative survival rate (P <0.05). No adverse events occurred in both groups (intraoperative death, complications of surgery) occurred in both groups in the incidence of adverse events, P> 0.05, no significant difference. Conclusion: The effect of preoperative adjuvant chemotherapy for non-small cell lung cancer is significant, which can improve the resection rate and postoperative survival rate, which is worthy of clinical promotion.