为了了解流脑多糖菌苗普种的效果及其经济效益,1985年在唐河县用病史前瞻性调查方法,对22,648名15岁以下农村儿童调查结果:免疫组11,735人,发病6人,发病率5.11/万;对照组10,913人,发病52人,发病率47.65/万。菌苗保护率95%的可信限为89.29±4.39%,效果指数1:9.32,X~2=40.05,P<0.01。效益成本的比值(QC)为1:6.70。多糖菌苗的流行病学效果与国内外用实验流行病学方法所得的结果基本相符,但节省人力和时间。 In order to understand the effect and economic benefits of melobacillar spirulina, a survey of 22,648 rural children under 15 years of age was conducted in Tanghe County in 1985: 11,735 people in the immunization group, with a disease incidence of 6 Rate of 5.11 / million; control group of 10,913 people, the incidence of 52 people, the incidence rate of 47.65 / million. The confidence limit of 95% of the vaccine was 89.29 ± 4.39%, the effect index was 1: 9.32, X ~ 2 = 40.05, P <0.01. The cost-benefit ratio (QC) is 1: 6.70. The epidemiological effect of polysaccharide vaccine basically agrees with that obtained by experimental epidemiological methods at home and abroad, but it saves manpower and time.