更年期综合症是由于卵巢功能减退而引发的全身综合性病理改变,由于病因复杂,临床表现缺乏特异性,所以制作动物模型较困难。我们在参考了病人的临床表现及病理改变后设计出以X线照射大鼠卵巢造成人工更年期综合症模型,得到了良好的效果,并观察了谷维素注射液对这些大鼠的治疗作用。 Climacteric syndrome is due to ovarian dysfunction caused by the systemic general pathological changes, due to complicated etiology, lack of specificity of clinical manifestations, making animal models more difficult. We reference the patient’s clinical manifestations and pathological changes after the design of the X-ray irradiation ovaries induced artificial climacteric syndrome model, obtained good results, and observed the oryzanol injection in these rats therapeutic effect.