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我们自1998年以来,应用灵杆菌素治疗恶性肿瘤化疗后所致白细胞减少,取得了较好的效果。1 材料与方法1.1 临床资料1.1.1 病例 1998年1月～2001年6月,共60例患者。其中急性淋巴细胞性白血病(ALL)24例,急性髓细胞性白血病(AML)16例,何杰金氏病(HD)4例,非何杰金氏淋巴瘤(NHL)6例,原发性肺癌4例,晚期胃癌4例,乳腺癌术后2例。其中男39例,女21例,年龄12～68岁,中位数37岁。所有病例均接受联合化疗,且化疗后外周血白细胞数显著下降,中性分叶核粒细胞绝对值<0.5×10~9/L,伴有发热,此时给予灵杆菌素治疗。
We since 1998, the application of leptin treatment of malignant neoplasms after chemotherapy leukopenia achieved good results. 1 Materials and Methods 1.1 Clinical data 1.1.1 cases from January 1998 to June 2001, a total of 60 patients. Among them, 24 cases were acute lymphoblastic leukemia (ALL), 16 cases were acute myeloid leukemia (AML), 4 cases were Hodgkin’s disease (HD), 6 cases were non-Hodgkin’s lymphoma (NHL) 4 cases of lung cancer, 4 cases of advanced gastric cancer and 2 cases of postoperative breast cancer. 39 males and 21 females, aged 12 to 68 years, median 37 years. All cases received combined chemotherapy, and the number of peripheral blood leukocytes decreased significantly after chemotherapy. The absolute value of neutrophil neutrophils was less than 0.5 × 10 ~ 9 / L, accompanied by fever.