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衰变加速因子(DAF)、膜辅蛋白(MC)、CD59是细胞膜上存在的3种补体下调因子,它们可保护宿主细胞不受本身补体系统的损伤,在异种器官移植方面具有重大的应用价值。本文讨论这3种因子的结构、特性及应用前景。
DAF, MC and CD59 are three kinds of complement down-regulation factors in cell membrane. They can protect host cells from their own complement system and are of great value in xenotransplantation. This article discusses the structure, characteristics and application prospects of these three factors.