牙髓组织中的细胞,包括成牙本质细胞和牙髓成纤维细胞,与其它有核细胞一样,一方面存在受遗传控制的细胞分裂、增殖的功能,另一方面也具有使细胞主动发生死亡的机制,即细胞凋亡,两者之间的动态平衡维持着牙髓组织的内环境稳定。我们已经研究了炎症刺激下牙髓组织中细胞凋亡的特点,本文讨论牙髓组织在增龄性变化中细胞凋亡和增殖的变化。 Cells in dental pulp, including odontoblasts and dental pulp fibroblasts, like other nucleated cells, have the function of genetically controlled cell division and proliferation on the one hand, and cell death on the other hand The mechanism of apoptosis, the dynamic balance between the two maintained the internal stability of pulp tissue. We have examined the characteristics of apoptosis in pulp cells stimulated by inflammation and this article discusses the changes in apoptosis and proliferation of pulp tissue during age-related changes.