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目的总结肝病患者希瓦菌感染的临床因素及耐药情况。方法回顾性分析2009年1月至2015年12月无菌部位希瓦菌培养阳性的肝病患者的临床资料,并采用表型实验和质谱仪对希瓦菌进行再鉴定。结果共收集7例非重复希瓦菌感染者的资料,其中希瓦菌所致血流感染2例,腹膜炎4例,胆道感染1例。经鉴定,4株为海藻希瓦菌,3株为腐败希瓦菌。在临床治疗过程中,希瓦菌易对碳青霉烯类药物不敏感,而对左氧氟沙星和阿米卡星敏感。结论希瓦菌可引起重症肝病患者多个无菌部位的感染,左氧氟沙星或阿米卡星可取得较好的抗菌效果。
Objective To summarize the clinical factors and drug resistance of Hepatitis B virus infection in patients with liver diseases. Methods The clinical data of patients with positive Hepatitis B virus culture in the aseptic area from January 2009 to December 2015 were retrospectively analyzed. The phenotype and mass spectrometry were used to re-identify the species. Results A total of 7 cases of non-repetitive Chlamydia spp. Infection were collected. Among them, 2 were bloodstream infection caused by Shewanella, 4 were peritonitis and 1 was biliary tract infection. Identified, 4 strains of seaweed chihwa bacteria, 3 strains of chilli vanillia. Shewa is susceptible to carbapenems and clinically sensitive to levofloxacin and amikacin. Conclusion Shewanella can cause multiple infections in patients with severe liver disease, levofloxacin or amikacin can achieve better antibacterial effect.