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采用吡喃糖氧化酶（ＰＲＯＤ）法检测１，５－脱水山梨醇（１，５－ＡＧ）浓度。正常人（７５例）为２９．８４±９．９１ｍｇ／Ｌ，正常下限为１３．５ｍｇ／Ｌ；ＩＧＴ者（１８例）为１８．６１±４．６５ｍｇ／Ｌ；糖尿病患者（１８８例）为６．５８±４．２６ｍｇ／Ｌ，三者间呈显著性差异（Ｐ＜０．００１），糖尿病患者１，５－ＡＧ值比正常人低４５％。１，５－ＡＧ分别与空腹血糖（ｒ＝－０．７０６０）、２４小时尿糖（ｒ＝－０．８５３３）、果糖胺（ｒ＝－０．６７５９）、糖化血红蛋白（ｒ＝－０．５９１１）均呈显著负相关，提示１，５－ＡＧ可用作糖尿病监测新指标。同时还证明１，５－ＡＧ尚可反映过去一周内短期的平均血糖水平，因此弥补了过去缺乏短期指标之不足。
The concentration of 1,5-AG (1,5-AG) was detected by the pyranose oxidase (PROD) method. The normal range was 29.84 ± 9.91mg / L in normal subjects, the normal lower limit was 13.5mg / L, 18.61 ± 4.65mg / L in IGT patients and 188 in diabetic patients were 6.58 ± 4.26mg / L, there was a significant difference between the three (P <0.001), 1,5-AG in diabetic patients lower than normal 45%. (R = -0.7060), 24-hour urine glucose (r = -0.8533), fructosamine (r = -0.6759) and HbA1c (r = -0. 5911) showed a significant negative correlation, suggesting 1,5-AG can be used as a new indicator of diabetes monitoring. It also proves that 1,5-AG can still reflect the short-term average blood glucose level in the past week, thus making up for the lack of short-term indicators in the past.