论文部分内容阅读
采用胶囊导管经皮穿刺血管成形术,扩张狭窄及闭塞的动脉(或搭桥的静脉)已有确实的疗效,且有安全和费用低廉的优点。但有关其作用机制尚未完全阐明。本文结合临床和实验性血管成形术,复习了已经提出的五种可能机制:1)粥样硬化斑块受压变实;2)斑块再分布和再塑形;3)斑块成分栓塞;4)动脉壁成形伸展和5)噬细胞清除斑块—血管成形术创伤所引起的愈合反应,并对此一一作出评价。第一,胶囊膨胀使动脉腔当即扩大,首先想到的机制是对斑块的直接压迫。有如脚踩后积雪受压变实形成足迹或钉子钉入木头穿孔,使其容积缩小。同样,斑块也可受压,其液体和固体成分被挤出。但斑块和动脉与雪和木头不同,具有弹性,当
Percutaneous puncture angioplasty using a capsule catheter expands the stenotic and occluded arteries (or bypass grafts) with proven efficacy and safety and cost-effectiveness. However, its mechanism of action has not yet been fully elucidated. In this review, five possible mechanisms have been reviewed in combination with clinical and experimental angioplasty: 1) compression of atherosclerotic plaques; 2) redistribution and remodeling of plaques; 3) plaque embolism; 4) Arterial wall formation and extension, and 5) Phagocytic plaque-angioplasty trauma-induced healing reactions were evaluated. First, the expansion of the capsule to immediately expand the arterial lumen, the first thought of the mechanism is the direct compression of the plaque. As the foot after the snow pressure into the formation of footprints or nail nail into the wood perforation, to reduce its volume. Similarly, the plaque can also be pressed, the liquid and solid components are squeezed out. But the plaques and arteries are different from snow and wood, with elasticity