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目的探讨米非司酮联合散结镇痛胶囊治疗子宫腺肌病的临床效果。方法 120例确诊为子宫腺肌病患者,根据就诊号码单双号随机分为单纯西药治疗组和中西药联合治疗组,每组60例。单纯西药治疗组采用米非司酮治疗,中西药联合治疗组采用米非司酮联合散结镇痛胶囊治疗,经过3个月经周期治疗,对治疗效果进行对照总结分析。结果单纯西药治疗组显效10例,有效30例患者,无效20例,临床总有效率为66.67%,中西药联合治疗组显效16例,有效38例,无效6例,临床总有效率为90.00%;中西药联合治疗组治疗总有效率明显高于单纯西药治疗组,差异有统计学意义(P<0.05)。结论米非司酮联合散结镇痛胶囊治疗子宫腺肌病,能够标本兼治,具有疗效明显、安全性能高、显效时间短等优势,值得临床广泛推广应用。
Objective To investigate the clinical efficacy of mifepristone combined with Sanjiezhuotong Capsule in the treatment of adenomyosis. Methods One hundred and twenty patients diagnosed as adenomyosis were randomly divided into simple western medicine group and traditional Chinese and western medicine group according to the single and double numbers of visiting doctor, with 60 cases in each group. Western medicine group treated with mifepristone alone, combined treatment of traditional Chinese and western medicine group with mifepristone combined Sanjie analgesic capsule treatment, after 3 menstrual cycle treatment, the treatment effect were compared and analyzed. Results Western medicine alone was effective in 10 cases, effective in 30 cases and ineffective in 20 cases. The total clinical effective rate was 66.67%. Sixteen cases were treated with combination of traditional Chinese medicine and western medicine, 38 cases were effective and 6 cases were ineffective. The total effective rate was 90.00% ; The total effective rate of combination therapy group was significantly higher than that of western medicine alone group, the difference was statistically significant (P <0.05). Conclusion Mifepristone combined with Sanjiezhitong capsule can treat adenomyosis, which can treat both the symptoms and the root causes. It has the advantages of obvious curative effect, high safety performance and short effective time, which is worthy of wide application in clinic.