目的:分析连云港市病残儿童资料,通过孕前优生健康检查干预其近五年病残儿父母再生育,预防病残儿的发生风险。方法:对连云港市2008―2012年经过医学鉴定的病残儿的资料进行分析,比较其五年间数量、地区、性别分布、疾病顺位变化等,发放调查问卷了解其在生育病残儿之前的基本情况;再次怀孕后有无优生指导、超生排畸、唐筛、妊娠结局、分娩方式等调查,分析干预效果。结果:近五年通过医学鉴定符合病残儿童标准的1 046例五年间无明显变化;城区较农村多;男性较女性多;疾病顺位排序先天性心脏病位于第一位。通过干预,收回问卷中先天性心脏病父母再生育72例均为正常儿,其次脑瘫患儿父母再生育35例均为正常儿。结论:病残儿鉴定父母通过孕前优生健康检查,完成整个孕前保健、风险评估到个性化咨询指导一系列干预后再生育均为正常儿,干预效果明显,减少了不良妊娠结局的发生,对预防和降低再次生育病残儿的发生非常重要。 Objective: To analyze the data of sick and disabled children in Lianyungang and to prevent the disabled children from being reborn by the prenatal health examination of their prenatal care in the past five years. Methods: The data of sick and disabled children who were medically identified in Lianyungang from 2008 to 2012 were analyzed, and the distribution of their numbers, regions, gender and the change of disease status were compared over the past five years. Questionnaires were issued to find out the number of disabled children before birth Basic conditions; after pregnancy again without eugenics guidance, ultrasound row abnormalities, Tang sieve, pregnancy outcome, mode of delivery and other surveys, analysis of the intervention effect. Results: In the past five years, there were no significant changes in 1 046 patients who met the criteria of disabled children through medical examination in the past five years. There were more urban areas than rural areas; more males than females; and the order of disease was ranked first in congenital heart disease. Through intervention, 72 cases of conception of congenital heart disease were retrieved from the questionnaire and all of them were normal children. Conclusion: The disabled children identified through prenatal health checkup of eugenics to complete the entire pre-pregnancy health care, risk assessment to a series of individual counseling and counseling after a series of interventions are normal childbirth, the intervention effect is obvious, reducing the incidence of adverse pregnancy outcomes, prevention And reduce the incidence of re-birth sick children is very important.