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日本东京大学理学部冈田教授等通过烟草细胞制备作用于人脑的生理活性物质获得成功。这种极微量物质,可给脏器以很大影响。冈田使用增殖力极强的“烟草花叶病毒(TMV)”在酒草上感染,平均每公斤烟草能增殖这种病毒2g。在合成这种病毒的“外衣”蛋白质遗传因子的后面,连结上合成脑啡肽(enkephalin)物质的遗传因子。脑啡肽存在于人脑等部位,是由5个氨基酸连结的肽物质,有抑制疼痛作用。将含有脑啡肽遗传因子的TMV接种到烟草培养细胞上,随着TMV的增殖,脑啡肽也形成。若接种到烟草上,也同样能形成脑啡肽。脑啡肽能通过化学方法合成,也能用大肠菌制取。本研究通过植物不但能生成脑啡肽,也能应用于生产其它药用肽类及激素。冈田成功地将TMV的遗传因子汲入烟草中,
Okada, a professor of science at the University of Tokyo in Japan, succeeded in producing physiologically active substances that act on the human brain through tobacco cells. This kind of trace substance, can have a great influence on organs. Okada uses a very fertile “Tobacco Mosaic Virus (TMV)” to infect grass wine, and on average 2g of this virus can be multiplied per kilogram of tobacco. Behind the “coat” protein genetic elements that synthesize this virus are linked genetic elements that synthesize enkephalin. Enkephalin is present in the brain and other parts of the brain, is composed of five amino acid peptide material, inhibit pain. TMV containing enkephalin gene was inoculated on tobacco cultured cells, and enkephalin also formed with the proliferation of TMV. If inoculated into tobacco, also can form enkephalin. Enkephalin can be chemically synthesized, but also can be used to produce coliform bacteria. In the present study, not only enkephalin can be produced in plants, but also other medicinal peptides and hormones. Okada succeeded in drawing the genetic elements of TMV into tobacco,