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脂质纳米制剂包括纳米乳、固体脂质纳米粒、纳米结构脂质载体以及脂质体等剂型,近年来在眼科应用发展迅速。本文通过查阅、归纳和整理近期的文献,分析上述4种脂质纳米制剂的特点,介绍其在眼部给药方面的应用进展,并综述和介绍了此类制剂所用辅料、制备工艺及表征方法。
Lipid nanomaterials including nanoemulsion, solid lipid nanoparticles, nanostructured lipid carriers and liposomes and other dosage forms, in recent years in the rapid development of ophthalmology. This article reviews, summarizes and summarizes recent literature, analyzes the characteristics of the four lipid nano-formulations described above, describes its application in ophthalmic administration, and reviews and describes the excipients, preparation techniques and characterization methods .