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采用本室建立的标记抗生物素-生物素酶联免疫试验及间接酶免疫试验进行血清与肝组织前S蛋白检测。慢性乙肝病毒感染者肝组织前S_1和前S_2的检出率略高于血清标本;血清前S_1和前S_2的相对含量与同一患者肝内前S_1前S_2阳性细胞数有一定正相关关系,但与前S_1、前S_2表达方式及其肝脏病理变化无明显关系。
The labeled anti-biotin-biotin enzyme-linked immunosorbent assay and indirect enzyme immunoassay were used to detect the serum and liver pre-S protein. The detection rate of pre-S 1 and pre-S 2 in liver tissue of chronic hepatitis B virus infection was slightly higher than that of serum samples. The relative content of pre-S 1 and pre-S 2 had positive correlation with the number of pre-S 1 pre-S 2 positive cells in the same patient There was no significant relationship between the expression of S_2 and preS_2 and the pathological changes of hepatic cells.