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目的探讨扬州市妇幼保健院使用热毒宁注射液不良反应发生的原因及预防措施。方法对扬州市妇幼保健院2009年收集到的27例热毒宁不良反应报告,分别从患者性别、年龄、不良反应发生潜伏期、给药剂量、临床表现、不良反应处理情况、关联性情况等方面进行统计分析。结果 27例热毒宁注射液不良反应中,以男性儿童占最多;临床表现主要为药物性皮疹、过敏,其次为胃肠道反应,过敏性休克等严重不良反应发生较少。结论加强药物不良反应(ADR)监测及相关知识宣传的力度,增强医务人员的责任感,可减少ADR的发生。
Objective To investigate the causes and preventive measures of adverse reactions caused by Reveduining Injection in Yangzhou MCH Hospital. Methods A total of 27 cases of adverse drug reactions were collected from Yangzhou MCH hospital in 2009, including gender, age, latent period of adverse reactions, dosage, clinical manifestations, adverse reactions and related situations conduct statistical analysis. Results The adverse reactions of 27 cases of Rendunning injection were dominated by male children. The main clinical manifestations were drug-induced rash and allergy, followed by gastrointestinal reactions and less serious adverse reactions such as anaphylactic shock. Conclusion To strengthen the monitoring of ADR and related knowledge publicity, enhance the sense of responsibility of medical staff and reduce the occurrence of ADR.