“药辅合一”是中药制剂学中独特的用药理念、制药经验与哲学智慧。然而,一直存在传统经验整理不够,现代基础研究不足的缺陷。为此,阐述“药辅合一”的理论内涵与基本特点,初步总结了中药制剂中常见的“药辅合一”现象及物理化学基础,探讨“药之为辅”与“辅之为药”的设计应用规律,并结合现代研究实例分析“药辅合一”思想对中药新辅料、新技术与新制剂研究的指导价值,以期从传统经验中探寻思路,促进传统知识与现代研究的融合,推动中药制剂学的传承与创新。 “Medication combined with a ” is a unique drug concept in traditional Chinese medicine preparation, pharmaceutical experience and philosophical wisdom. However, there are always shortcomings of insufficient traditional experience and insufficient basic research in modern times. Therefore, the author elaborates the theoretical connotation and basic characteristics of “medicine combined with one ”, initially summarizes the common “medicine combined with a ” phenomenon and physicochemical basis of traditional Chinese medicine preparation, And “supplement medicine” design rules, combined with modern research case analysis “medicine combined with one ” thinking on the guidance of traditional Chinese medicine new excipients, new technologies and new preparations research, with a view to explore from the traditional experience Train of thought, promote the integration of traditional knowledge and modern research, and promote the inheritance and innovation of traditional Chinese medicine preparation.