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目的筛选并优化诊断需氧菌性阴道炎的几个指标,评价其诊断价值。方法 474例疑似需氧菌性阴道炎患者经Donders AV评分和5种预成酶联合检测2种方法诊断。ROC曲线分析5种预成酶、p H值、WBC计数诊断需氧菌性阴道炎的价值。筛选并优化p H值、H2O2浓度、WBC计数的不同组合诊断需氧菌性阴道炎的价值。结果 Donders AV评分诊断患需氧菌性阴道炎患者387例。p H值、WBC计数、H2O2浓度是诊断需氧菌性阴道炎的3个较好指标。以p H>4.5、H2O2浓度<2μmol/L且WBC计数≥1+/hpf为诊断标准或H2O2浓度<2μmol/L且WBC计数≥2+/hpf为诊断标准,诊断需氧菌性阴道炎的特异性为100.0%,灵敏度也高达97.4%。此标准与Donders AV评分诊断需氧菌性阴道炎阳性率比较,差异无统计学意义(P>0.05)。结论将p H值、H2O2浓度、WBC计数组合诊断需氧菌性阴道炎的方法简便、实用、快速、灵敏度高,对临床需氧菌性阴道炎诊治有较好的指导作用。
Objective To screen and optimize the diagnosis of aerobic bacterial vaginitis several indicators to evaluate its diagnostic value. Methods A total of 474 patients with suspected aerobic bacterial vaginosis were diagnosed by Donders AV score and 5 preformed enzymes. ROC curve analysis of five kinds of preformed enzyme, p H value, WBC count diagnostic value of aerobic bacterial vaginosis. Screening and optimizing p H value, H2O2 concentration, WBC count of different combinations of diagnostic aerobic bacterial vaginitis value. Results 383 patients with aerobic bacterial vaginosis were diagnosed by Donders AV score. p H value, WBC count, H2O2 concentration are three good indicators of diagnosis of aerobic bacterial vaginosis. The diagnosis of aerobic bacterial vaginosis was based on the diagnostic criteria of p H> 4.5, the concentration of H2O2 <2 μmol / L and WBC count ≥1 + / hpf or the concentration of H2O2 <2 μmol / L and WBC count ≥2 + / hpf Specificity of 100.0%, sensitivity as high as 97.4%. This standard and Donders AV score diagnosis of aerobic bacterial vaginosis positive rate, the difference was not statistically significant (P> 0.05). Conclusion The combination of p H value, H 2 O 2 concentration and WBC count in the diagnosis of aerobic bacterial vaginitis is simple, practical, rapid and sensitive. It has a good guidance for the diagnosis and treatment of clinical aerobic bacterial vaginitis.