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首先制备了表面氨基化的SiO2纳米颗粒,再分别将发绿色和红色荧光的CdTe QDs按比例组装于其表面,最后,用SiO2包覆SiO2-CdTe QDs纳米颗粒,实现了多步制备复合(SiO2-CdTe QDs)/SiO2编码荧光纳米颗粒。(SiO2-CdTe QDs)/SiO2编码荧光纳米颗粒不仅化学、光学性能稳定,而且还有利于与生物基团结合。另外,探讨了复合(SiO2-CdTe QDs)/SiO2编码荧光纳米颗粒与血红蛋白质结合的情况。从而为复合(SiO2-CdTe QDs)/SiO2编码荧光纳米颗粒作为生物探针在生化分析的应用奠定了一定的基础。
Firstly, the surface-aminated SiO2 nanoparticles were prepared and then the green and red fluorescence-emitting CdTe QDs were assembled on the surface. Finally, the SiO2-CdTe QDs nanoparticles were coated with SiO2, -CdTe QDs) / SiO2 encoding fluorescent nanoparticles. (SiO2-CdTe QDs) / SiO2-encoded fluorescent nanoparticles are not only chemically and optically stable, but also help to combine with biological groups. In addition, the combination of SiO2-CdTe QDs / SiO2 fluorescent nanoparticles with hemoglobin was discussed. Therefore, it has laid a foundation for the application of composite nanoparticles (SiO2-CdTe QDs) / SiO2 fluorescent nanoparticles as bio-probes in biochemical analysis.