奴夫卡因是最常用的局部麻醉剂。据文献资料,药物过敏性休克的发生率,奴夫卡因居第四位,仅次于青霉素、安乃近和链霉素。作者观察70例不能耐受奴夫卡因的病人,接受奴夫卡因以后的临床表现:荨麻疹20例,Quincke氏(局限性)水肿4例,皮炎8例,支气管哮喘发作2例,软组织水肿4例,眩晕3例,晕厥23例,过敏性休克6例。以后都在全麻下进行手术。报告一个典型病例,男,36岁,患左颌下和咽旁间隙蜂窝织炎,局麻下行脓肿切开术,用1%奴夫卡因15ml局部浸润麻醉,注射后5～7分钟,病人皮肤急剧苍白,主诉呼吸困难、恶心、躁动、心动过速、血压下降。口腔粘膜、软腭、声带急剧水肿,紧急气管插 Nuvocaine is the most commonly used local anesthetic. According to the literature, the incidence of anaphylactic shock drug, Nuvocaine ranked fourth, second only to penicillin, metamizole and streptomycin. The authors looked at 70 patients who could not tolerate lovavanine and accepted subsequent clinical manifestations of lovavacine: 20 cases of urticaria, 4 cases of Quincke’s (localized) edema, 8 cases of dermatitis, 2 cases of bronchial asthma attack, 2 cases of soft tissue 4 cases of edema, 3 cases of dizziness, 23 cases of syncope, 6 cases of anaphylactic shock. After surgery under general anesthesia. A typical case was reported in men, 36, suffering from cellulitis of the left subpharyngeal and parapharyngeal space, abdominopelvic ablation under local anesthesia, topical anesthesia with 15 ml of 1% Nuvivacaine, and 5 to 7 minutes after injection Dramatic skin pale, complained of dyspnea, nausea, agitation, tachycardia, blood pressure. Oral mucosa, soft palate, vocal cord rapid edema, emergency tracheal plug