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目的:提高大家对以神经系统表现为主的双硫仑样反应认识,避免误诊误治。方法:临床分析一例因酒精擦浴导致以神经系统表现为主的双硫仑样反应。结果:静脉滴注头孢哌酮停药第五天,酒精擦浴导致以神经系统表现为主的双硫仑样反应,抗过敏治疗有效。结论:头孢菌素类是临床较为常用抗生素,但应用该药期间直接或间接接触含酒精类物质时,个别患者会出现以神经系统表现为主的双硫仑样反应。如对双硫仑反应认识不足,有可能造成严重后果。
Objectives: To raise awareness of disulfiram-like responses to neurological manifestations and avoid misdiagnosis and mistreatment. Methods: A case analysis of disulfiram-like reactions that predominantly manifested in the nervous system due to rubbing with alcohol was clinically analyzed. Results: On the fifth day after intravenous cefoperazone withdrawal, alcohol rubbing bath led to the disulfiram-like reaction mainly manifested in the nervous system, and anti-allergy treatment was effective. Conclusion: Cephalosporins are clinically more commonly used antibiotics, but the application of the drug during direct or indirect exposure to alcohol-containing substances, individual patients will appear mainly in the performance of the nervous system disulfiram-like response. Inadequate understanding of the disulfiram response may have serious consequences.