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目的:通过对90例妊娠期肝内胆汁淤积症患者的临床病例进行分析探讨该病对母婴的临床危害。方法:选择2014年12月-2015年12月期间共收治ICP患者共计75例,对所有病例进行回顾性分析,观察产妇经治疗后生产发生的相关不良预后的情况。结果:75例孕妇中早产14例,胎儿窘迫发生9例,胎儿生长受限6例,羊水过少5例,产后出血2例。90例产妇中19例阴道分娩,占21.11%,剖宫产71例,占78.89%,8例婴儿为低体重儿,6例发生新生儿窒息,经过治疗后产妇及婴儿均健康出院,无死亡以及不良预后病例。结论:肝内胆汁淤积症对胎儿有较大的危害,能够引起早产、胎儿窘迫等情况发生,但经过积极治疗,其预后较好。
Objective: To analyze the clinical cases of 90 cases of intrahepatic cholestasis of pregnancy in patients with maternal and child clinical hazards. Methods: A total of 75 patients with ICP were selected from December 2014 to December 2015. All the cases were retrospectively analyzed to observe the related adverse prognosis after maternal treatment. Results: Among 75 pregnant women, 14 were premature, 9 were fetal distress, 6 were fetal growth restriction, 5 were oligohydramnios and 2 were postpartum hemorrhage. Among the 90 cases, 19 cases were vaginal delivery, accounting for 21.11%. Cesarean section was 71 cases, accounting for 78.89%. 8 cases of infants were of low birth weight and 6 cases of neonatal asphyxia. After treatment, both maternal and infant were discharged without any death As well as poor prognosis. Conclusion: Intrahepatic cholestasis has a greater risk to the fetus, which can cause premature birth and fetal distress. However, after active treatment, the prognosis is good.