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为了定量测试脑膜瘤WHO分级法的价值,作者应用倍体分类、增殖指数和S期细胞比率三项参数进行分析,发现这三项指标与WHO分级密切相关。脑膜瘤异形细胞、坏死、核分裂及脑浸润的出现与肿瘤WHO分级增加和肿瘤复发密切相关。这些结果特别对肿瘤的异质性和测量技术差异问题给予小心评价。
To quantify the value of the WHO classification of meningiomas, the authors used the three parameters of the ploidy classification, proliferation index and S-phase cell ratio to analyze and found that these three indexes are closely related to the WHO classification. The incidence of meningioma-like cells, necrosis, mitosis and brain infiltration is closely related to the WHO classification and tumor recurrence. These results give a special assessment of differences in tumor heterogeneity and measurement techniques.