中药复方Ⅲ号抗癌淋巴道转移的实验研究

来源 :中国实验方剂学杂志 | 被引量 : 0次 | 上传用户:chiale
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目的 :为中药复方 号抗癌转移的临床应用提供理论依据。方法 :小鼠子宫颈癌 U14 (腹水型 )接种于昆明小鼠左后肢爪垫皮下造成淋巴道转移模型 ,用形态学方法观察了各站淋巴结的转移情况。结果 :中药复方 号可抑制 U14 转移 ,大、中、小各剂量组及环磷酰胺的淋巴结转移抑制率分别为 :79.1%、6 6 .6 %、6 8.8%、4 3.3%。结论 :中药复方 号可一定程度抑制癌淋巴道转移。 Objective : To provide a theoretical basis for the clinical application of anticancer metastasis of traditional Chinese medicine compound number. METHODS: Murine cervical carcinoma U14 (ascites type) mice were inoculated into the subcutaneous tissue of the left hind paw of Kunming mice and lymph node metastasis model was established. The metastasis of lymph nodes was observed by morphological methods. RESULTS: Compound No. of traditional Chinese medicine could inhibit the metastasis of U14. The inhibitory rates of lymph node metastasis of large dose, medium dose, small dose, and cyclophosphamide were 79.1%, 66.6%, 68.8%, and 43.3%, respectively. Conclusion : Chinese medicine compound number can inhibit lymphatic metastasis to a certain extent.
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