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硝硫氰胺“7505”(4-硝基-4-异硫氰基-二苯胺)系武汉市医药工业研究所合成的一种广谱驱虫药。湖北省医学科学院寄生虫病防治研究所1976年曾先后两次试治钩虫感染患者,均表明有较好疗效。本文报道目的是再次治疗一组钩虫病例,对该药三种不同治疗方案进行临床评价,并与小剂量灭虫宁合并驱虫净相比较,选取一种疗效高、副反应轻、使用方便的治疗方案,供临床应用参考。一、材料与方法1.于1977年4～5月在宜都县××大队及××中学进行普查钩虫的基础上,选择部分虫卵阳性病例,作洪氏法虫卵计数。凡每克粪便虫卵在200个以上者作为观察对象,同时取
Nitrosaminamide “7505” (4-nitro-4-isothiocyanato-diphenylamine) is a broad-spectrum anthelmintic synthesized by Wuhan Institute of Pharmaceutical Industry. Institute of Parasitic Diseases, Hubei Academy of Medical Sciences Institute in 1976 has twice tried hookworm infection in patients, have shown a good effect. The aim of this paper is to treat a group of hookworm again and to evaluate the efficacy of three different treatment regimens. Compared with the low-dose dexamethasone and deworming net, we selected one with high curative effect, light side reaction and easy to use Treatment options for clinical reference. I. Materials and Methods 1. From April to May 1977, on the basis of the census of hookworms conducted by ×× Brigade and ×× Middle School in Yidu County, some egg-positive cases were selected for egg counting by Hirschsprung’s method. Where per stool eggs in more than 200 as observed, while taking