自Metchnikoff于十九世纪初叶描述了吞噬现象以来,对巨噬细胞功能的了解长期停留在清道夫细胞(Scavenger cell)这一概念上。近年来,发现巨噬细胞除了噬菌、杀菌、抗肿瘤和清除损伤和衰老细胞的功能外,还可产生一种集落刺激因子(colony stimulating factor),或许参与对粒细胞生成的控制。在免疫反应中,巨噬细胞还具有调节免疫应答的功能,它与T细 Since Metchnikoff described phagocytosis in the early 19th century, the understanding of macrophage function has long stuck to the concept of a scavenger cell. In recent years, macrophages have been found to produce, in addition to phagocytosis, bactericidal, antitumor and clearance of damaged and senescent cells, a colony stimulating factor that may be involved in the control of granulocytopoiesis. In the immune response, macrophages also have the ability to regulate the immune response, it and T fine