已知甲基多巴能诱发抗核抗体和红斑性狼疮细胞的生成,但此时患者均无系统性红斑狼疮的临床表现,作者报告1例因使用甲基多巴引起的狼疮样综合征。患者女,48岁,因全身虚弱,不适,晨起周身僵硬,关节痛及雷诺氏现象12个月入院。两年来,患者因高血压用甲基多巴250mg 每日3次。入院时血压180/ It is known that methyldopa can induce the production of antinuclear antibodies and erythro-lupus erythematosus cells, but none of the patients present with clinical manifestations of systemic lupus erythematosus. The authors reported 1 case of lupoid-like syndrome caused by the use of methyldopa. The female patient, 48 years old, was fatigued due to general weakness and discomfort. She was stiff in the morning and had joint pain and Raynaud’s phenomenon for 12 months. Two years, patients with hypertensive methylcholine 250mg 3 times a day. Admission of blood pressure 180 /