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2-氯脱氧腺苷(2-cdA)是一种嘌呤类似物,近年用于临床。作者应用2-cdA治疗复发难治的慢性淋巴细胞增殖性疾病,取得了良好的效果。作者报道2-cdA治疗39例慢性淋巴细胞增殖性疾病,均为经1～4疗程化疗后复发或耐药者,中位年龄61岁,其中男24例,女14例,其中B慢淋(B-CLL)19例,B幼淋细胞白血病(B-
2-Chloro-deoxyadenosine (2-cdA) is a purine analog used clinically in recent years. The authors apply 2-cdA treatment of refractory chronic lymphocytic proliferative disease, and achieved good results. The authors reported 39 patients with chronic lymphocytic proliferative disease treated with 2-cdA, all of whom were relapsed or resistant to chemotherapy after 1 to 4 courses of chemotherapy. The median age was 61 years, including 24 males and 14 females, including B B-CLL) 19 cases, B lymphocytic leukemia (B-