分子生物学研究证明，正常细胞中原癌基因变异，导致细胞正常增殖和分化紊乱，引起细胞恶变，最终形成癌瘤。与肺癌相关的原癌基因，已发现多种，具有同源碱基序列的Ｋｒａｓ、Ｈｒａｓ和Ｎｒａｓ的ｒａｓ族基因活化，主要见于非小细胞型肺癌。其突变检出率约３０％... Molecular biology studies have demonstrated that mutations in proto-oncogenes in normal cells result in normal proliferation and differentiation of cells, causing cell malignancy, and ultimately the formation of cancerous tumors. Oncogenes associated with lung cancer have been found to be diverse, with K-ras, H-ras, and N-ras ras family genes having homologous base sequences activated, mainly found in non-small cell lung cancer. Its mutation detection rate is about 30%...