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目的:了解社区老年患者的潜在性不适当用药情况,评价Beers准则在我国社区的适用性,为社区临床合理用药提供可借鉴的方法。方法:对石家庄市416例社区多重用药的老年非住院患者的潜在用药风险进行综合评价。结果:患者平均年龄72.7±7.1岁,平均用药4.9±1.6种,药物不良反应发生率24.5%,潜在性不适当用药的发生率为14.7%,用药数量、服用潜在性不适当用药和发生药物不良反应呈正相关(r=0.498,P<0.01;r=0.729,P<0.01)。结论:Beers准则在预测药物不良反应上具有重要的应用价值,中国可借鉴之构建老年安全用药指南。
Objective: To understand the potential inappropriate use of drugs in elderly patients in the community, to evaluate the applicability of Beers’ guidelines in our community and to provide a reference for clinical use of drugs in the community. Methods: A total of 416 community-based multi-drug use of elderly non-hospitalized patients in Shijiazhuang City, a potential risk assessment for comprehensive evaluation. Results: The average age of patients was 72.7 ± 7.1 years, the average medication was 4.9 ± 1.6, the rate of adverse drug reactions was 24.5%, the potential incidence of inappropriate medication was 14.7%, the number of medication, the improper use of medication and the occurrence of drug abuse The response was positively correlated (r = 0.498, P <0.01; r = 0.729, P <0.01). Conclusion: The Beers criterion has important application value in predicting adverse drug reactions. China can learn from it to construct a guidebook on elderly drug safety.