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目的探索人类免疫缺陷病毒(HIV)感染或艾滋病(AIDS)患者口腔真菌定植状况及菌种分布,为HIV感染或AIDS患者真菌感染防治提供理论依据。方法选择2013年6—12月在新疆医科大学第一附属医院感染科就诊的HIV感染或AIDS患者30例,由口腔科采用咽拭子法收集口腔分泌物,通过真菌培养实验分析口腔真菌定植状况。结果 30例HIV感染或AIDS患者中,阳性带菌者19例,阳性率为63.3%。阳性带菌者年龄2~52岁;其中男13例(68.4%)、女6例(31.6%);维吾尔族15例(78.9%),汉族4例(21.1%)。阳性带菌者中携带白色念珠菌15例(78.9%)。结论白色念珠菌为HIV感染或AIDS患者口腔真菌定植的主要菌种。阳性带菌者年龄分布广泛。
Objective To explore oral fungal colonization and distribution of oral fungus in patients with human immunodeficiency virus (HIV) infection or AIDS, and to provide theoretical basis for the prevention and treatment of fungal infection in HIV-infected or AIDS patients. Methods Thirty patients with HIV infection or AIDS were selected from the Department of Infectious Diseases, the First Affiliated Hospital of Xinjiang Medical University from June to December in 2013. Oral secretions were collected by stomatology using throat swab method. The fungal culture was used to analyze the oral fungal colonization . Results Of the 30 cases of HIV infection or AIDS, 19 were positive carriers, the positive rate was 63.3%. The positive carriers were aged 2 to 52 years old, including 13 males (68.4%) and 6 females (31.6%), 15 (78.9%) Uygurs and 4 (21.1%) Han males. Positive carriers carry Candida albicans in 15 cases (78.9%). Conclusion Candida albicans is the main species for oral fungal colonization in HIV-infected or AIDS patients. Positive carriers are widely distributed in age.