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目的凝血四项及D-二聚体的检测在肝硬化患者中的应用体会。方法选取郑州卷烟厂康复医院2013年10月~2015年1月进行凝血四项和D-二聚体检测的患者100例,其中被诊断为肝硬化的患者50例作为研究组,指标正常的体检患者50例作为对照组,对两组患者凝血四项及D-二聚体各指标进行统计分析。结果肝硬化组凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)和凝血酶时间(TT)较对照组延长,纤维蛋白(FIB)浓度较对照组低,D-二聚体(D-Dimer)浓度较对照组高(P<0.05)。结论进行凝血四项及D-二聚体的检测,对于评价肝硬化患者体内凝血状况、预估出血倾向,具有重要的临床价值。
Objective To investigate the detection of four coagulation and D-dimer in patients with liver cirrhosis. Methods 100 cases of coagulation four and D-dimer test in Zhengzhou Cigarette Factory Rehabilitation Hospital from October 2013 to January 2015 were selected, of which 50 cases were diagnosed as liver cirrhosis as study group, Fifty patients were used as the control group, and the four indexes of coagulation and D-dimer in two groups were statistically analyzed. Results Prothrombin time (PT), activated partial thromboplastin time (APTT) and thrombin time (TT) in patients with cirrhosis were longer than those in the control group, and fibrin (FIB) D-Dimer concentration higher than the control group (P <0.05). Conclusion The detection of four coagulation and D-dimer has important clinical value in evaluating the coagulation status and predicting the bleeding tendency in patients with cirrhosis.