目的　探讨大面积烧伤病人切痂植皮时机的选择。方法　将 15例行切痂植皮的大面积烧伤病人随机分为两组 ,治疗组 8例行休克期切痂植皮治疗 ,对照组 7例休克期过后 (即非休克期 )行切痂植皮治疗。观察两组病人伤后第 3天的生命体征、尿量、输血量、并发症 ,住院天数及治愈率。结果　治疗组比对照组伤后第 3天生命体征平稳 ,术中每 1%切痂面积输血量少 ,并发症少 ,住院天数少 ,无死亡病例 ,治愈率高。结论　休克期切痂及早地去除了坏死组织 ,减轻了机体中毒反应 ,降低了感染发生率 ,从而提高了治愈率 ,对成功救治大面积烧伤病人极为有益。 Objective To explore the timing of escharectomy in large area burn patients. Methods Fifteen patients with extensive burn patients undergoing eschar excision were randomly divided into two groups. Eight patients in the treatment group underwent skin incision and excision in the shock stage. Seven patients in the control group received eschar excision after shock period (ie, non-shock period). The vital signs, urine output, blood transfusion, complications, days of hospitalization and cure rate were observed on the 3rd day after injury in both groups. Results Compared with the control group, the vital signs in the treatment group were stable on the third day after injury. The transfusion volume per 1% of the escharectomy area was less in the treatment group than in the control group. There were fewer complications, fewer days of hospitalization and no deaths. The cure rate was higher. Conclusion Excision of the sciosis at shock stage removes the necrotic tissue early, reduces the toxic reaction and reduces the incidence of infection, thus improving the cure rate. It is extremely beneficial for successful treatment of large area burn patients.