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随着生活水平的不断提高，糖尿病（ DM）发病率逐年增加，而DM对冠心病影响很大，可能导致更严重的管腔狭窄、长病变、钙化、多支病变等，也影响冠心病患者的远期预后，导致远期主要不良心脏事件的发生，这严重影响患者的生存率和容易导致急性心血管事件的发生，可能与DM引起动脉粥样硬化斑块不稳定相关。为了给临床治疗提供较为准确的参考，现对采用血管内光学相干断层成像观察DM对冠状动脉粥样硬化斑块不稳定性的影响做一综述。“,”With the continuous improvement of living standards ,the incidence of diabetes has increased year by year ,and has a great impact on coronary heart disease .This may lead to more serious stenosis ,long lesions ,calcification ,and multivessel disease .It may also affect the long-term prognosis of patients with coronary heart disease and lead to long-term MACE events,which seriously affects patient survival rate and easily leads to the occurrence of acute cardiovascular events .This may be related to diabetes and can cause unstable atherosclerotic plaque .In order to provide a more accurate reference for clinical treatment ,a review was conducted on how the effect on OCT was used to ob-serve the impact of diabetes on coronary atherosclerotic plaque instability .