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目的:研究山绿茶三种不同炮制品对麻醉猫正常血压的影响。方法:以复方罗布麻片和硝苯地平片为阳性对照,采用家猫颈动脉插管后,稳定1 h,记录药前血压,采用十二指肠给药,观察药后30、60、90、120、150、180、210、240 m in的血压值。结果:山绿茶的三种不同炮制品对麻醉猫正常血压均有降压作用。其中大剂量(10.8 g/kg)的降压效果较小剂量(5.4 g/kg)出现快、作用强、维持时间长。效果最好的为自炒品大剂量,降压效果给药后90 m in开始,药后2 h降压效果与硝苯地平比无显著性差异(P>0.05),血压下降率大于复方罗布麻片。烘干品小剂量对血压没影响。结论:山绿茶的三种不同炮制品对麻醉猫正常血压均有降压作用,其中大剂量的降压效果较小剂量强、快、持久,效果最好的为自炒品大剂量。
Objective: To study the effects of three different processed products of green tea on normal blood pressure in anesthetized cats. METHODS: Compound apocynum tablets and nifedipine tablets were used as positive controls. After the carotid arteries of domestic cats were used for intubation, they were stabilized for 1 h. Pre-drug blood pressure was recorded. Duodenal administration was used. 30, 60, and 90 post-drug administration were observed. Blood pressure values of 120, 150, 180, 210, 240 in. RESULTS: The three different processed products of the mountain green tea all had antihypertensive effect on normal blood pressure in anesthetized cats. The high-dose (10.8 g/kg) antihypertensive effect (5.4 g/kg) appeared to be faster, stronger, and longer. The best effect was the high dose of fried products, and 90 m in. after the antihypertensive effect began. There was no significant difference in the antihypertensive effect compared with nifedipine after 2 hours (P>0.05). The rate of blood pressure decrease was higher than that of Rob Hemp tablets. A small dose of dried product had no effect on blood pressure. Conclusion: The three different processed products of shan shan green tea have antihypertensive effect on the normal blood pressure of anesthetized cats. The large-dose antihypertensive effect is smaller, stronger, faster and longer lasting. The best effect is high-dose self-propelled products.