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在苏联,有关甾类激素的問題被視作目前科学研究工作中以及医药工業生产方面的重要問題之一。近年来,有关甾类激素的全合成,即以比較簡單的易于合成的有机物为原料来合成甾类激素的工作已进行了很多。在苏联科学院有机化学研究所,曾由院士直接領导进行了自乙烯基乙炔合成一系列甾类化合物,类似甾类化合物的多环化合物的工作,虽然至今尚未發現有較强生理效应者,但这些研究成果,在甾类化合物的化学發展上是有着很重大的作用的。在全苏化学制药研究所激素化学部主任领导下,也在进行部份与甾类激素全合成有关的工作,如合成环戊烷过氫菲烃化合物,Δ~(4,9)3(I),使有可能合成不含C_3,C_(17)位甲基的甾
In the Soviet Union, the problem of steroid hormones is regarded as one of the important issues in scientific research and in the pharmaceutical industry. In recent years, the overall synthesis of steroid hormones, that is, relatively simple and easy to synthesize organic compounds as raw materials to synthesize steroid hormones have been carried out a lot. In the Institute of Organic Chemistry of the Soviet Academy of Sciences, academicians led by the academicians directly from the vinyl acetylene synthesis of a series of steroids, steroid compounds similar to the work of the polycyclic compounds, although no strong physiological effects have so far been found, These research results in the chemical development of steroids has a very significant role. Under the leadership of the director of the Department of Hormonal Chemistry at the Institute of Chemistry and Pharmacy of Soochow University, there are also some work related to the total synthesis of steroid hormones, such as the synthesis of cyclopentane hydroperoxide compounds, Δ ~ (4,9) 3 (I ), Making it possible to synthesize steroids without C_3, C_ (17) methyl groups