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为研究孕酮受体 (PR)与米非司酮抗早孕出血残留蜕膜和绒毛的关系 ,用免疫细胞化学LSAB法显示出血后刮出组织 ( 1 9例 )中的PR。发现PR在子宫内膜基质细胞、腺上皮细胞、肌上皮细胞、血管内皮细胞和平滑肌细胞多呈阳性或强阳性 ,在残留绒毛呈弱阳性 ,而在残留蜕膜细胞多为阴性。PR在子宫内膜和残留蜕膜中的分布有显著性差异 (P <0 .0 1 )。提示药流后蜕膜和绒毛残留与蜕膜中孕酮受体无关 ,而内膜中孕酮受体的作用有待进一步研究。
In order to investigate the relationship between progesterone receptor (PR) and residual decidua and chorion in patients with early pregnancy induced by mifepristone, the PR in the scraped tissues (19 cases) after hemorrhage was demonstrated by the immunocytochemical LSAB method. Found in the endometrial stromal cells of PR, glandular epithelial cells, myoepithelial cells, vascular endothelial cells and smooth muscle cells were mostly positive or strongly positive, in the residual villi was weakly positive, and most of the remaining decidual cells were negative. The distribution of PR in the endometrium and residual decidua was significantly different (P <0.01). Prompts after decidua and villi residual fluid and decidual progesterone receptor has nothing to do, and the role of intimal progesterone receptor needs further study.