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目的探讨糖化血红蛋白(HbA1c)、空腹血糖(FPG)和餐后2 h血糖(2 h PG)的相关性。方法受试者为2010年1月至10月326例进行血糖和HbA1c检测的患者。血糖由葡萄糖氧化酶法测定,HbA1c由硼酸亲和层析法测定。结果 FPG与2 h PG显示了高度相关性,回归方程为Y=3.17+0.336X(r=0.866,P<0.01),当餐后2 h血糖为11.1 mmol/L时,FPG计算得6.9 mmol/L,当FPG为7.0 mmol/L时,餐后2 h血糖计算为11.08。且FPG和2 h PG血糖对于HbA1c的回归方程分别为Y=1.11X+0.1(r=0.809,P<0.01)和Y=2.97X-7.06(r=0.809,P<0.01),当HbA1c分别为6.0%和6.1%时,FPG分别计算得6.76 mmol/L和6.87 mmol/L,而2 h PG分别为10.71 mmol/L和11.07 mmol/L。结论 HbA1c与FPG和2 h PG之间有显著相关性,可以用HbA1c≥6.1%这个指标来筛查糖尿病患者。
Objective To investigate the relationship between HbA1c, fasting blood glucose (FPG) and 2 h postprandial blood glucose (2 h PG). Methods The subjects were 326 patients who underwent blood glucose and HbA1c tests between January 2010 and October 2010. Blood glucose was measured by glucose oxidase method, HbA1c by boric acid affinity chromatography. Results FPG showed a high correlation with 2 h PG with a regression equation of Y = 3.17 + 0.336X (r = 0.866, P <0.01). When glucose was 11.1 mmol / L at 2 h postprandial, FPG calculated 6.9 mmol / L, when the FPG was 7.0 mmol / L, 2 h postprandial blood glucose was calculated as 11.08. The regression equation of FPG and 2 h PG blood glucose to HbA1c were Y = 1.11X + 0.1 (r = 0.809, P <0.01) and Y = 2.97X-7.06 FPG were calculated to be 6.76 mmol / L and 6.87 mmol / L respectively at 6.0% and 6.1% compared to 10.71 mmol / L and 11.07 mmol / L for 2 h PG respectively. Conclusions There is a significant correlation between HbA1c and FPG and 2 h PG, which can be used to screen diabetic patients with HbA1c≥6.1%.