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目的：研究纤溶酶治疗急性脑梗死的临床疗效。方法选取2012年8月—2014年8月成都市龙泉驿区第一人民医院收治的急性脑梗死患者106例，随机分为观察组和对照组，每组53例。对照组给予常规疗法，观察组在常规疗法基础上给予纤溶酶治疗，采用美国国立卫生研究院卒中量表（ NIHSS）评价两组患者的神经功能缺损情况，比较两组患者的临床疗效。结果观察组患者总有效率（94.34%）高于对照组（73.58%），治疗后观察组NIHSS评分低于对照组，差异有统计学意义（ P﹤0.05）。结论纤溶酶治疗急性脑梗死的疗效显著，可促进患者神经功能恢复。“,”Objective To study the clinical effect of fibrinolysin in treating acute cerebral infarction. Methods From August 2012 to August 2014 in the First HosPital of Longquanyi District,a total of 106 Patients with acute cerebral infarc-tion were selected and randomly divide into observation grouP and control grouP,53 cases in each grouP. Control grouP were trea-ted with routine treatment,observation grouP were treated with fibrinolysin on the basis of routine treatment,neurologic imPair-ment of the two grouPs were evaluated by National Institutes of Health Stroke Ccale( NIHSS),the clinical effect between the two grouPs were comPared. Results The total effective rate of observation grouP ( 94. 34%) was higher than control grouP (73. 58%),the NIHSS scores of study grouP were lower than those of control grouP after treatment,the differences were statis-tically significant(P﹤0. 05). Conclusion Fibrinolysin has significant effect in treating acute cerebral infarction,can im-Prove neurologic imPairment of Patients.