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目的:探究沙格列汀治疗老年糖尿病用药效果。方法:选择2013年3月-2015年3月的152例老年DM患者为研究对象,将其分成两组,对照组使用二甲双胍进行治疗,观察组使用沙格列汀进行治疗,两个月后,观察两组患者的临床治疗效果。结果:在接受为期2个月的治疗之后,对照组患者的心肌酶变化情况基本恢复正常,明显低于对照组患者,P<0.05.观察组患者的肾脏功能与肝脏功能明显好于对照组,组间数据存在统计学差异,P<0.05.两组患者治疗期间不良反应情况无统计学差异,P>0.05。结论:对于轻度至中度或者无肝肾功能损伤的老年糖尿病患者,使用沙格列特进行治疗,可以取得较为满意的临床效果。值得进一步同推广。
Objective: To explore the effect of saxagliptin on senile diabetes mellitus. Methods: A total of 152 senile DM patients from March 2013 to March 2015 were selected as study subjects and divided into two groups. The control group was treated with metformin. The observation group was treated with saxagliptin. Two months later, The clinical effects of two groups were observed. Results: After 2 months of treatment, the changes of myocardial enzymes in the control group returned to normal, which were significantly lower than those in the control group (P <0.05) .The renal function and liver function in the observation group were significantly better than those in the control group There was statistical difference between the two groups (P <0.05) .There was no significant difference in adverse reactions between the two groups during treatment (P> 0.05). CONCLUSIONS: For elderly diabetic patients with mild to moderate or no hepatic and renal dysfunction, the use of sialogliptin may achieve satisfactory clinical outcomes. Worth further promotion with.