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目的探讨胶质肉瘤的影像学表现与临床病理特点。方法回顾性分析经手术病理证实的脑胶质肉瘤8例的CT、MR I表现和临床病理所见,并复习文献。结果7例位于幕上区,小脑1例,8例CT扫描5例为低等混杂密度,2例为低密度,1例为稍高密度,增强扫描为不规则强化,其内见囊变及坏死。3例行MR I检查,T1W I为低信号,T2W I为稍高混杂信号或高信号。增强扫描为不均匀强化,边界清楚,水肿明显。组织学检查,肿瘤由胶质母细胞和梭形细胞2种成分组成,免疫组化检查8例,脑胶质细胞成分GFAP为阳性,梭形细胞成分GFAP为阴性。结论脑胶质肉瘤少见,临床上无特异性,CT、MR I表现虽有一定特点,但确诊依靠病理检查。
Objective To investigate the imaging features and clinicopathological features of glioma sarcoma. Methods A retrospective analysis of 8 patients with glioma confirmed by surgery and pathology showed CT and MR findings and reviewed the literature. Results Seven cases were located in the supratentorial area, one was in the cerebellum, five in the eight cases were of low density, two in low density, one in slightly elevated density and enhanced in irregular enhancement. Necrosis. Three routine MRI examination, T1WI low signal, T2WI slightly higher mixed signal or high signal. Enhanced scan for uneven enhancement, clear boundary, edema significantly. Histological examination showed that the tumor consisted of two components of glioblastoma and spindle cells. There were 8 cases of immunohistochemical examination, GFAP of glial cells was positive and GFAP of spindle cells was negative. Conclusions Glial sarcoma is rare and clinically nonspecific. Although CT and MR I have certain characteristics, the diagnosis depends on the pathological examination.