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播散性单纯疱疹主要见于细胞免疫缺陷者,病死率很高。随着抗病毒药物的发展,如何早期发现疱疹病毒的播散以便给予及时有效的治疗已成为重要问题。作者回顾性分析了经尸检证实诊断的临床和病理资料,总结出本病的诊断标准,并经前瞻性临床验证,结果令人满意。1972～1981年,经病理检查确诊为播散性单纯疱疹病毒感染者共20例,年龄自2个月～4岁,15例原有营养不良,4例处于麻疹恢复期(其中2例并存营养不良)。17例有典型的口腔或皮肤局部单纯疱疹,另1例
Disseminated herpes simplex found in patients with cellular immunodeficiency, high mortality. With the development of antiviral drugs, how to detect the spread of the herpes virus in order to provide timely and effective treatment has become an important issue. The authors retrospectively analyzed the clinical and pathological data confirmed by autopsy, concluded the diagnostic criteria of the disease, and prospective clinical validation, the results were satisfactory. From 1972 to 1981, there were 20 confirmed cases of disseminated herpes simplex virus infection by pathology. The patients were from 2 months to 4 years old, 15 were malnourished, and 4 were in the convalescent period (2 of them coexisted bad). 17 cases of typical oral or dermal skin herpes simplex, the other 1 case