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为探讨糖尿病患者动脉粥样硬化的高发机制，检测了44例糖尿病患者和50例健康者血脂、载脂蛋白、低密度脂蛋白中甘油三酯、总胆固醇和氧化型低密度脂蛋白水平。结果发现低密度脂蛋白中甘油三酯及甘油三酯／胆固醇比值升高为糖尿病患者脂质异常的显著特征。血清氧化型低密度脂蛋白水平及氧化程度显著升高，其氧化程度同低密度脂蛋白脂质组成相关。提示糖尿病患者动脉粥样硬化的高发生率同其低密度脂蛋白组成异常及氧化修饰水平相关联。
To investigate the high incidence of atherosclerosis in diabetic patients, the levels of triglyceride, total cholesterol and oxidized low density lipoprotein in blood lipids, apolipoproteins and low density lipoproteins were detected in 44 diabetics and 50 healthy subjects. The results showed that low-density lipoprotein triglyceride and triglyceride / cholesterol ratio increased diabetes patients with significant features of lipid abnormalities. Serum levels of oxidized low-density lipoprotein and oxidation increased significantly, the degree of oxidation is related to the composition of low-density lipoprotein lipids. This suggests that the high incidence of atherosclerosis in diabetic patients correlates with the abnormalities of LDL composition and the level of oxidative modification.